Red Wine Attacks Bioinflammation: Possibly Prevents Hearing Loss & Cognitive Decline

A study on red wine and hearing loss came out a couple of years ago. I have searched to see if any part of the report has been retracted, challenged or changed, and found nothing. The Department of Otolarynology-Head & Neck Surgery at Henry Ford Hospital, Detroit, Michigan, published the findings of the grape properties of resveratrol in mice, in a journal named for that department. Once again, resveratrol is being lauded. Added to the long list of benefits from red wine and red grapes, it may be possible to prevent hearing loss and cognitive decline. According to the study, resveratrol attacks bioinflammation, which is also indicated in Alzheimer’s disease, cancer and aging.



Resveratrol is a very powerful chemical that seems to protect against the body’s inflammatory process as it relates to aging, cognition and hearing loss. …

Hearing loss affects nearly one in five Americans. For most, hearing steadily declines with age. Noise-induced hearing loss, too, is a growing medical issue among American troops, with more than 12 percent returning home from Iraq and Afghanistan with significant hearing loss.

Noise-induced hearing loss not only impacts a person’s ability to hear, it can cause difficulties with sleep and communication, and even raises the risk for heart disease by increasing a person’s blood pressure, lipids and blood sugar.

Dr. Seidman and his colleagues have published multiple papers exploring noise-induced hearing loss, as well as the use of resveratrol, a grape constituent noted for its antioxidant and anti-inflammatory properties.

The latest study focuses the inflammatory process as it relates to aging, cognition and hearing loss.

It was designed to identify the potential protective mechanism of resveratrol following noise exposure by measuring its effect on cyclooxygenase-2 (or COX-2, key to the inflammatory process) protein expression and formation of reactive oxygen species, which plays an important role in cell signaling and homeostasis.

The study reveals that acoustic overstimulation causes a time-depended, up-regulation of COX-2 protein expression. And, resveratrol significantly reduces reactive oxygen species formation, inhibits COX-2 expression and reduces noise-induced hearing loss following noise exposure in rats.

“We’ve shown that by giving animals resveratrol, we can reduce the amount of hearing and cognitive decline,” notes Dr. Seidman.

Ultimately, these findings suggest that resveratrol may exert a protective effect from noise-induced hearing loss by the inhibition of COX-2 expression and reactive oxygen species formation, although other mechanism may also be involved. Source:

Resveratrol, an antioxidant, is not found in the grape skins of white, gold or green grapes –– only in the skins of black, purple and red grapes. Find the study abstract here. Don’t let words like “cyclooxygenase-2 (a key to the inflammation process) keep you away.

As always, wine and all alcoholic drinks should be consumed in moderation, which is generally one five ounce serving for women, and two for men, until a man reaches the age of 65 –– when one serving is considered “moderate.”

Some Biblical Wisdom from IntoWine – 1st Timothy 5:23:


The Bible often makes references to the value of wine for health and enjoyment. Our ancestors knew of its aid to health when drunk in moderation. In fact, up until the 18th century, wine played a central role in medicine. Wine inhibits the growth of all micro-organisms that are the cause of disease in man. Because of its alcohol and acid content, they simple die in it.

In the modern world, wine is accepted as a healthful drink. Only in the United States are we once again, beginning to rediscover its value to society. For many years, we focused in the dangers of overindulgence. To be sure, there are dangers to the over-use of wine. The Bible too, warns of this. But in moderation, it is a healthy beverage.

(NIV) “Stop drinking only water, and use a little wine because of your stomach and your frequent illnesses.”

(KJV) “Drink no longer water, but use a little wine for thy stomach’s sake and thine often infirmities.”

Related: Red Wine: Type 2 Diabetes and HDL Cholesterol –– A Significant Study

Linked in Theo Spark’s Daily Spark – lots of interesting headlines. Read them here.

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